MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06717(PPP2R2B antibody) at dilution of 1:500
IP Result of PPP2R2B antibody (IP: FNab06717, 4ug; Detection: FNab06717 1:500) with SH-SY5Y cells lysate 2000ug.
Immunofluorescent analysis of HeLa cells using FNab06717 (PPP2R2B antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
背景介绍
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).