Polyglutamine-binding protein 1 (PQBP-1)|38 kDa nuclear protein containing a WW domain (Npw38)|Polyglutamine tract-binding protein 1|PQBP1|NPW38 antibody
货号:
FNab06743
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
PQBP1 antibody
货号
FNab06743
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
polyglutamine binding protein 1
别称
Polyglutamine-binding protein 1 (PQBP-1)|38 kDa nuclear protein containing a WW domain (Npw38)|Polyglutamine tract-binding protein 1|PQBP1|NPW38 antibody
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06743(PQBP1 antibody) at dilution of 1:500
背景介绍
Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.