mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06915(PTGER3 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab06915(PTGER3 Antibody) at dilution of 1:200
背景介绍
Receptor for prostaglandin E2(PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems(By similarity).