mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06947(PTPRR antibody) at dilution of 1:500
背景介绍
Sequesters mitogen-activated protein kinases(MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus(By similarity).