human brain tissue were subjected to SDS PAGE followed by western blot with FNab06996(RAB14 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab06996(RAB14 Antibody) at dilution of 1:50
背景介绍
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes(By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.