human colon tissue were subjected to SDS PAGE followed by western blot with FNab07016(RAB32 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lung cancer using FNab07016(RAB32 antibody) at dilution of 1:50
背景介绍
Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission(PubMed:12186851). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis(PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis(PubMed:23084991). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes(By similarity).