mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07031(RAB3GAP2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab07031(RAB3GAP2 Antibody) at dilution of 1:50
背景介绍
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily(RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.