mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab07046(RAB8B antibody) at dilution of 1:1000
IP Result of anti-RAB8B (IP:FNab07046, 4ug; Detection:FNab07046 1:1000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab07046(RAB8B Antibody) at dilution of 1:50
背景介绍
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells(By similarity).