fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab07269(RGS2 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07269(RGS2 antibody) at dilution of 1:50
背景介绍
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).