HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07321(RMI1 antibody) at dilution of 1:500
IP Result of anti-RMI1 (IP:FNab07321, 3ug; Detection:FNab07321 1:1500) with HeLa cells lysate 3800ug.
Immunohistochemistry of paraffin-embedded human gliomas using FNab07321(RMI1 antibody) at dilution of 1:100
背景介绍
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions(DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.