产品
本公司产品仅供体外研究使用，不用于临床诊断
RYK antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- RYK antibody
- 货号
- FNab07548
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- RYK receptor-like tyrosine kinase
- 别称
- Tyrosine-protein kinase RYK|RYK|JTK5A antibody
- UniProt ID
- P34925
- 分子量
- 68 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07548(RYK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab07548(RYK antibody) at dilution of 1:50
Immunofluorescent analysis of SH-SY5Y cells using FNab07548 ( RYK Antibody) at dilution of 1:50 and Alexa Fluor488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
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