HeLa cells were subjected to SDS PAGE followed by western blot with FNab07613(SASS6 antibody) at dilution of 1:1000
IP Result of anti-SASS6 (IP: FNab07613, 4ug; Detection: FNab07613 1:1000) with HeLa cells lysate 800ug.
Immunohistochemistry of paraffin-embedded human kidney slide using FNab07613(SASS6 Antibody) at dilution of 1:50
背景介绍
Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification(PubMed:22020124).