NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab07775(SF3A2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab07775(SF3A2 antibody) at dilution of 1:50
背景介绍
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.