产品
本公司产品仅供体外研究使用，不用于临床诊断
SMN1 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- SMN1 antibody
- 货号
- FNab08033
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG1
- Clone ID
- 3D2
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- survival of motor neuron 2, centromeric
- 别称
- Survival motor neuron protein|Component of gems 1|Gemin-1|SMN1|SMN|SMNT antibody
- UniProt ID
- Q16637
- 分子量
- 38 kDa
验证实验
- 验证实验
- ELISA, WB, IF
- 建议稀释比例
- WB: 1:1000-1:6000; IF: 1:50-1:500
验证图片
A375 cells were subjected to SDS PAGE followed by western blot with FNab08033(SMN antibody) at dilution of 1:3000
Immunofluorescent analysis of ( -20℃ Ethanol) fixed HEK-293 cells using FNab08033 (SMN antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
- 背景介绍
- The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.
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