PC-13 cells were subjected to SDS PAGE followed by western blot with FNab08039(SMOX antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using FNab08039(SMOX Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
背景介绍
Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform(isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.