HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08057(SNAP25 antibody) at dilution of 1:10000
IP Result of anti-SNAP25 (IP: FNab08057, 2ug; Detection: FNab08057 1:500) with mouse brain tissue lysate 2000ug.
Immunofluorescent analysis of PC-12 cells using FNab08057 (SNAP25 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
背景介绍
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.