HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08103(SOD1 antibody) at dilution of 1:1500
IP Result of anti-SOD1 (IP:FNab08103, 3ug; Detection:FNab08103 1:1500) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab08103(SOD1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
背景介绍
Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.