Nesprin-2|KASH domain-containing protein 2 (KASH2)|Nuclear envelope spectrin repeat protein 2|Nucleus and actin connecting element protein (Protein NUANCE)|Synaptic nuclear envelope protein 2 (Syne-2)|SYNE2|KIAA1011|NUA antibody
货号:
FNab08436
反应性:
Human
宿主:
Rabbit
验证实验:
ELISA, WB
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
SYNE2 antibody
货号
FNab08436
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
spectrin repeat containing, nuclear envelope 2
别称
Nesprin-2|KASH domain-containing protein 2 (KASH2)|Nuclear envelope spectrin repeat protein 2|Nucleus and actin connecting element protein (Protein NUANCE)|Synaptic nuclear envelope protein 2 (Syne-2)|SYNE2|KIAA1011|NUA antibody
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08436( SYNE2 Antibody) at dilution of 1:600
背景介绍
Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear(TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for centrosome migration to the apical cell surface during early ciliogenesis.