Y79 cells were subjected to SDS PAGE followed by western blot with FNab08440(SYNM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab08440(SYNM antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab08440 (SYNM antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
背景介绍
Type-VI intermediate filament(IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.