mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08578(TDRD3 Antibody) at dilution of 1:300
IP Result of anti-TDRD3 (IP:FNab08578, 3ug; Detection:FNab08578 1:1000) with HeLa cells lysate 3800ug.
背景介绍
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation(H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs(GAR) in dimethylarginine-containing proteins.