HeLa cells were subjected to SDS PAGE followed by western blot with FNab08601(TESC antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab08601(TESC Antibody) at dilution of 1:200
背景介绍
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.