HeLa cells were subjected to SDS PAGE followed by western blot with FNab08619(TFAP2C antibody) at dilution of 1:1000
IP Result of anti-TFAP2C (IP:FNab08619, 4ug; Detection:FNab08619 1:1000) with HeLa cells lysate 2800ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08619(TFAP2C Antibody) at dilution of 1:400 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
背景介绍
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.