THO complex subunit 7 homolog|Functional spliceosome-associated protein 24 (fSAP24)|Ngg1-interacting factor 3-like protein 1-binding protein 1 (NIF3L1-binding protein 1)|hTREX30|THOC7|NIF3L1BP1 antibody
货号:
FNab08670
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
THOC7 antibody
货号
FNab08670
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
THO complex 7 homolog(Drosophila)
别称
THO complex subunit 7 homolog|Functional spliceosome-associated protein 24 (fSAP24)|Ngg1-interacting factor 3-like protein 1-binding protein 1 (NIF3L1-binding protein 1)|hTREX30|THOC7|NIF3L1BP1 antibody
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08670(THOC7 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human kidney using FNab08670(THOC7 antibody) at dilution of 1:100
背景介绍
Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production.