HeLa cells were subjected to SDS PAGE followed by western blot with FNab08817(TNFAIP1 antibody) at dilution of 1:3000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab08817( TNFAIP1 antibody) at dilution of 1:300
背景介绍
Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.