Tumor protein 63 (p63)|Chronic ulcerative stomatitis protein (CUSP)|Keratinocyte transcription factor KET|Transformation-related protein 63 (TP63)|Tumor protein p73-like (p73L)|p40|p51|TP63|KET|P63|P73H|P73L|TP73L antibody
货号:
FNab08880
反应性:
Human
宿主:
Mouse
验证实验:
ELISA, WB
克隆性:
monoclonal
亚型:
IgG1
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
TP63 antibody
货号
FNab08880
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
2A3
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
tumor protein p63
别称
Tumor protein 63 (p63)|Chronic ulcerative stomatitis protein (CUSP)|Keratinocyte transcription factor KET|Transformation-related protein 63 (TP63)|Tumor protein p73-like (p73L)|p40|p51|TP63|KET|P63|P73H|P73L|TP73L antibody
PC3 cells were subjected to SDS PAGE followed by western blot with FNab08880(P63 antibody) at dilution of 1:1000
背景介绍
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.