mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08973(TRIM22 Antibody) at dilution of 1:300
背景介绍
Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus(EMCV) and hepatitis B virus(HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity.