Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09133(TXNRD1 antibody) at dilution of 1:500
IP Result of anti-TXNRD1 (IP:FNab09133, 3ug; Detection:FNab09133 1:500) with Jurkat cells lysate 1500ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09133(TXNRD1 antibody) at dilution of 1:100
背景介绍
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.