产品
本公司产品仅供体外研究使用，不用于临床诊断
VIM antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥2100 |
| 50μg | RMB ¥1260 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- VIM antibody
- 货号
- FNab09410
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG1
- Clone ID
- 2G10
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- vimentin
- 别称
- Vimentin|VIM antibody
- UniProt ID
- P08670
- 分子量
- 55 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:1000-1:10000; IHC: 1:200-1:2000; IF: 1:20-1:200
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09410(Vimentin Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab09410(Vimentin Antibody) at dilution of 1:500.
- 背景介绍
- Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
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