Telomerase Cajal body protein 1|WD repeat-containing protein 79|WD40 repeat-containing protein antisense to TP53 gene (WRAP53beta)|WRAP53|TCAB1|WDR79 antibody
货号:
FNab09523
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IHC, IP
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
WRAP53 antibody
货号
FNab09523
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
WD repeat containing, antisense to TP53
别称
Telomerase Cajal body protein 1|WD repeat-containing protein 79|WD40 repeat-containing protein antisense to TP53 gene (WRAP53beta)|WRAP53|TCAB1|WDR79 antibody
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09523(WRAP53 antibody) at dilution of 1:300
IP Result of anti-WRAP53 (IP:FNab09523, 4ug; Detection:FNab09523 1:300) with HeLa cells lysate 2480ug.
Immunohistochemistry of paraffin-embedded human testis using FNab09523(WRAP53 antibody) at dilution of 1:100
背景介绍
Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.