mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab09566(YME1L1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09566(YME1L1 antibody) at dilution of 1:100
背景介绍
YME1L1(ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L,Meg-4,PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa.