Z-DNA-binding protein 1|DNA-dependent activator of IFN-regulatory factors (DAI)|Tumor stroma and activated macrophage protein DLM-1|ZBP1|C20orf183|DLM1 antibody
货号:
FNab09586
反应性:
Human
宿主:
Rabbit
验证实验:
ELISA, WB, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
ZBP1 antibody
货号
FNab09586
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
Z-DNA binding protein 1
别称
Z-DNA-binding protein 1|DNA-dependent activator of IFN-regulatory factors (DAI)|Tumor stroma and activated macrophage protein DLM-1|ZBP1|C20orf183|DLM1 antibody
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09586(ZBP1 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human liver cancer using FNab09586(ZBP1 antibody) at dilution of 1:50
背景介绍
Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor(IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3(By similarity).