Zinc finger CCCH-type with G patch domain-containing protein|G patch domain-containing protein 6|Zinc finger CCCH domain-containing protein 9|Zinc finger and G patch domain-containing protein|ZGPAT|GPATC6|GPATCH6|KIAA1847|ZC3H9|ZC3HDC9|ZIP antibody
货号:
FNab09634
反应性:
Human, Mouse
宿主:
Rabbit
验证实验:
ELISA, WB
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
ZGPAT antibody
货号
FNab09634
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
zinc finger, CCCH-type with G patch domain
别称
Zinc finger CCCH-type with G patch domain-containing protein|G patch domain-containing protein 6|Zinc finger CCCH domain-containing protein 9|Zinc finger and G patch domain-containing protein|ZGPAT|GPATC6|GPATCH6|KIAA1847|ZC3H9|ZC3HDC9|ZIP antibody
L02 cells were subjected to SDS PAGE followed by western blot with FNab09634(ZGPAT antibody) at dilution of 1:1000
背景介绍
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.