产品
本公司产品仅供体外研究使用，不用于临床诊断
PARP1 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- PARP1 antibody
- 货号
- FNab09939
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- protein A+G purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG1
- Clone ID
- 4A9
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- poly (ADP-ribose) polymerase 1
- 别称
- Poly [ADP-ribose] polymerase 1 (PARP-1)|ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1)|DNA ADP-ribosyltransferase PARP1|NAD(+) ADP-ribosyltransferase 1 (ADPRT 1)|Poly[ADP-ribose] synthase 1|Protein poly-ADP-ribosyltransferase PARP1|Poly [ADP-ribose] polymerase 1 antibody, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1 antibody, 89-kDa form|Poly [ADP-ribose] polymerase 1 antibody, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1 antibody, 24-kDa form|Poly [ADP-ribose] polymerase 1 antibody, 28-kDa form|PARP1|ADPRT|PPOL antibody
- UniProt ID
- P09874
- 分子量
- 115 kDa, 89 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09939(PARP1 Antibody) at dilution of 1:20000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09939(PARP1 antibody) at dilution of 1:600
Immunofluorescent analysis of HeLa cells using FNab09939 (PARP1 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
- 背景介绍
- PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
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