HLA class I histocompatibility antigen antibody, alpha chain G|HLA G antigen|MHC class I antigen G|Soluble HLA class I histocompatibility antigen antibody, alpha chain G (sHLA-G)|HLA-G|HLA-6.0|HLAG antibody
货号:
FNab09952
反应性:
Human
宿主:
Mouse
验证实验:
ELISA, WB, IHC
克隆性:
monoclonal
亚型:
IgG1
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
HLA-G antibody
货号
FNab09952
规格
100μg
状态
liquid
纯化方法
protein A+G purified
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
3C12
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
MHC class I antigen G
别称
HLA class I histocompatibility antigen antibody, alpha chain G|HLA G antigen|MHC class I antigen G|Soluble HLA class I histocompatibility antigen antibody, alpha chain G (sHLA-G)|HLA-G|HLA-6.0|HLAG antibody
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09952( HLA-G Antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human placenta tissue slide using FNab09952( HLA-G Antibody) at dilution of 1:200
背景介绍
Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.