产品

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TBP antibody

别称:GTF2D1 antibody, TF2D antibody, TFIID antibody
货号:FNab10263反应性:Human
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥750
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
TBP antibody
货号
FNab10263
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
TATA box binding protein
别称
GTF2D1 antibody, TF2D antibody, TFIID antibody
UniProt ID
P20226
分子量
37-43kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
Hela cells were subjected to SDS PAGE followed by western blot with FNab10263(TBP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10263(TBP antibody) at dilution of 1:100
背景介绍
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.