HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab10494( MMP16 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab10494( MMP16 Antibody) at dilution of 1:200
背景介绍
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.