Programmed cell death 6-interacting protein (PDCD6-interacting protein)|ALG-2-interacting protein 1|ALG-2-interacting protein X|Hp95|PDCD6IP|AIP1|ALIX|KIAA1375 antibody
货号:
FNab10988
反应性:
Human, Mouse, Rat
宿主:
Mouse
验证实验:
ELISA, WB
克隆性:
monoclonal
亚型:
IgG1
规格
价格
100μg
RMB ¥2100
50μg
RMB ¥1260
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
PDCD6IP antibody
货号
FNab10988
状态
liquid
纯化方法
protein A+G purified
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
8H4
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
programmed cell death 6 interacting protein
别称
Programmed cell death 6-interacting protein (PDCD6-interacting protein)|ALG-2-interacting protein 1|ALG-2-interacting protein X|Hp95|PDCD6IP|AIP1|ALIX|KIAA1375 antibody
Hela cells were subjected to SDS PAGE followed by western blot with FNab10988( PDCD6IP antibody) at dilution of 1:1000
背景介绍
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.