Raji cells were subjected to SDS PAGE followed by western blot with FNab07169(RBM22 antibody) at dilution of 1:1000
背景介绍
Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop(ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.